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    Worldwide Physicians’ Network for Lipolysis and Aesthetic Medicine

    WELCOME toe the new NEWSLETTER of NETWORK-Lipolysis

    Dear reader,

    The NETWORK-Lipolysis was founded more than 5 years with the aim of investigating the therapy of dissolving fat by injection, documenting the effects, and safeguarding against the hazards resulting from inappropriate use. Today, the NETWORK treatment protocol has become established throughout the world; our members are active in many fields, and there is an ongoing lively within the NETWORK about the further development of the protocol.

    Apart from lipolysis, another and far more extensive topic is gaining increasing prominence - one to which we, given our name, feel a special commitment - and that is the whole subject of networks. The term “network” is often used sloppily to describe any kind of loose association of people or parties. However, on closer examination of this subject, certain sides of it acquire a significance of which many sciences, including medicine, have only become aware through the publication of general theories about networks. Our Newsletter is therefore also an information medium that aims to do more than simply provide the latest news on injection lipolysis; it also strives for a completely new orientation through correct use of the term and concept of “network”.

    Newsletter EN No. 2 - 2009        

    In this edition, you can learn more about the following topics:
    Lipolysis insurance - update 
    Off-Label Use 
    The NETWORK – an independent institution
    5 Years of NETWORK-Lipolysis - part 2
    Side Effect Management
    New anaesthetic cream "Anesthesis C"
    PPC in medicine
    New products + special offers
    M.A.S.T.E.R.-Conference 2009 – FAT
    Workshop-Report (participant satisfaction)
    NETWORK-Lipolysis "en route"
    Forthcoming courses 2009

    Enjoy reading!
    Dirk Brandl
    Dirk Brandl
    (Speaker NETWORK-Lipolysis)
       Lipolysis insurance - update to top

    The NETWORK-Lipolysis has been able to conclude a group insurance policy for its members with a major British insurer specializing in cover for aesthetic therapies. We are currently working on broadening the scope beyond the European Union. Thanks to our efforts, we can also already offer liability cover for Australia and New Zealand, with other countries following soon. 

       Off-Label Use to top

    Necessity and freedom on a narrow line

    In Germany and a number of other countries, injection lipolysis is closely associated with the term “off-label use”.
    Off-label use means the use of a drug for indications other than or in addition to those stated by the manufacturer and approved by the licensing authority.


    The product Lipostabil N, for instance, which is used in lipolysis in Germany, is in fact registered for the treatment of fat embolism. Drugs in other countries containing the same active substances are licensed for treatment of the liver. The active substance PPC (polyenylphosphatidylcholine) is able to be indicated for such a broad spread of applications because it is a highly efficacious essential phospholipid with a therapeutic effect on the cell membranes. Botulin toxin A must also be seen in many cases as an off-label use, for even if it is now licensed for some manufacturers for aesthetic applications, the range of indications is very restricted (glabella fold).

    In many other areas of medicine, the number of off-label applications is growing constantly, for instance in oncology and paediatrics. The reason is that the drug manufacturers are becoming less and less willing to invest in the registration and licensing of products since the costs of this procedure have now reached a level that only the big multinationals are able to manage.

    An additional aspect is the hotly discussed issue of therapy individualization and the development of medication variants, which in the opinion of all experts will play a major role in future.

    The special aspect of off-label use is that it relieves the manufacturer of all liability, which has to be assumed by the treating physician instead. This is naturally a very pleasant position for the manufacturers; for the doctors looking for the best therapy option for their patients, on the other hand, it is a sword of Damocles constantly hanging above their heads.

    This issue has recently entered the spotlight of public attention. In It was a central topic, for instance, in the discussion round on German television chaired by popular TV host Sandra Maischberger on 5 May 2009. 

    A TV report on the medical platform DocCheck TV looks at the problems involved in detail. The conclusions from the standpoint of the medical profession, represented in this case by Dr. Ehnert,, a senior specialist in oncology at St. Georg Hospital in Hamburg, Meso-Flyercan be summed up as follows: Doctors who use a drug for an off-label use should 1. be able to back up the use by studies, 2. join forces with others to form specialist associations, and 3. participate in studies wherever possible. (Link to the TV report in German language)

    We, as the NETWORK-Lipolysis, can only support this statement by Dr. Ehnert. After all, the activities we have been engaged in now for several years absolutely mirror his demands: We have even initiated and funded studies out of the membership fees; some of our members have conducted their own studies and published the results; we gather data within the NETWORK on the safety of the therapy and investigate all side-effects that occur; and we encourage our members to conduct their own user observations.

       The NETWORK – an independent institution to top 

    Wouldn’t it be nice if a major pharmaceuticals company were to step in and support the work of the NETWORK? This is a question we have frequently asked ourselves over the years. It would allow us to cut our workshop costs and membership fees, improve the service we offer our members, and launch new developments.  

    5 Jahre NETZWERK-Lipolyse

    We were sometimes annoyed at the tight-fistedness of the manufacturers as it forced us to be financially creative while at the same time operating cautiously and conservatively, and also to demand prices for independent information - all of which did not exactly facilitate our market presence.

    Today, however, we are not only proud of our autonomy, it has, in fact, become our trademark. Absolute independence from all product suppliers and the objectivity of the information we provide are our LABEL, whether in the field of injection lipolysis or in the other areas of training we offer as part of our Globalhealth Academy. Even we ourselves were surprised to learn that our training concept for minimally invasive aesthetic therapies was something completely new. Before we started, we had not realized that training is normally in the hands of the firms who also supply the products; there is, therefore, no way that it can be truly objective.

       5 Years of NETWORK-Lipolysis  - Part 2 to top 

    A personal look back by Dirk Brandl

    (Part 1 you can find HERE)

    D. Brandl
    Part 2

    We soon had our first homepage in English and inquiries from interested medical practitioners. In June, I received an email from John Curran, a leading member of the BACD (British Association of Cosmetic Doctors), asking if it would not be possible for us to hold a workshop in London. 

    Up to then, with our classical marketing activities, we had only operated at local or national level.
    Now we had London in our sights, and up to that time I had only ever been on a plane two times in my life. Dr. Franz, as he soon become known - partly on account of his surname, which non-German speakers found unpronounceable - was, by contrast, a well-travelled man, for every year he had flown to faraway places with a group of people from his village under the label “Papa Doc Reisen”, and had therefore already been just about everywhere.

    July 2004 saw our first English workshop, which was held in the medical practice of Dr. Rita Rakus. The second workshop followed only a short time later, this time in the practice of Dr. Mervyn Patterson and his wife, Dr. Hillary Allen. From this day on, cooperation with the BACD developed very fruitfully as the therapy proved very popular with the patients in the UK.

    Hardly had we returned from London when we experienced our first major stir. We were informed that one of Dr Mervyn’s assistants, who had been treated by us, had had to be taken to hospital. The telephone wires between England, Germany and Austria were soon red hot. Dr. Franz also got in tough with the people at the hospital, for the treating physicians had noticed the large number of injection punctures and suspected that there could be a connection. For us, this was a very difficult situation. We had not yet known Dr. Franz long enough for a relationship of absolute trust to become established, and nobody could be completely sure that the therapy might not cause severe side-effects after all. The responsibility we all felt and the stress this situation caused for all of us were enormous. One wholly positive aspect, however, was the solidarity we experienced between all the people involved, whose only interest was in working together to get to the bottom of the problem. At no time were there any recriminations or reproaches. I would like to take this opportunity to thank Dr. Patterson and his wife Dr. Hillary Allen once more for their solidarity during that time.

    Luckily, in the course of the week, Dr. Patterson rang us to give us the all clear. It emerged that only the day before the treatment, the patient had returned from a holiday in Spain where she must have contracted salmonella poisoning. The relief we all felt is not hard to imagine.

    In 2004, we held 4 more workshops in London, the city becoming something of a home from home.

    But also in Germany, increasing numbers of patients were hearing about the therapy and calling us or sending us emails. During this first year, Dr. Franz was hard at work developing a therapy protocol as he disagreed with the protocol put forward by Patricia Rittes. He found this as having too many treatment sessions and the overall not being high enough, but at the same time the dose at each injection point being too high. The 14-day treatment interval also clashed with his own observations. He was able to draw on his many years of experience in use of the substance combination PPC-DOC contained in two drugs which were still licensed in Germany at that time, namely Essentiale (liver protection) and Lipostabil N® (fat embolism). He also collected and studied all the published literature on the effects and usages of the active substances. The result of his efforts was available in March 2004: The protocol was completely revised and rewritten on the basis of scientific and medical knowledge. At the same time, Dr. Franz was researching the possibilities for improving the combination of active substances.

    Subsequently, in June of that year, he was invited to a “Lipodissolve Convention” in Laguna Beach, USA, where he met Patricia Rittes for the first time. It was at this event that he also made the acquaintance of Dr. Diane Duncan, who in her capacity as a plastic surgeon had carried out studies of fat tissue and reached conclusions that concurred with Dr. Franz’s proposed changes to the treatment protocols.

    In November, we then invited all the physicians who had undergone training so far – numbering more than 160 – to our first Members Conference in Frankfurt. More than 75 of them took up the invitation.

    Three things in particular about this first members’ meeting have always remained in my memory: First, Dr. Franz presented his newly developed compound, triggering a heated discussion. Second, following the conference, various research groups were set up to examine individual aspects of the therapy more closely and - if possible and necessary - put forward proposals for new treatment protocols. And the third thing that has always stuck in my mind is the dinner that was held afterwards and that for me has become a symbol of what the NETWORK stands for: There were heated discussions, though with people from several different countries all seeking to collaborate in a spirit of solidarity and friendship, while towards the end, Patrick Treacy borrowed the guitar from the guitar soloist we had engaged, and we all ended up singing songs and celebrating an unforgettable ad hoc party.

    The end of the year 2004 was marked by the first major challenge that the still young NETWORK would have to face: In December of that year, we held a workshop for 12 doctors working for the Collagenics chain in London. Collagenics has most of its treatment rooms in cosmetic studios and, as we later learned, also in hairdressing salons run by the same management. We were warned by a number of British members of the aggressive marketing methods employed by this chain. The confrontation with this issue posed us with some fundamental questions: In what cases and to what extent should we as a NETWORK become involved, and where and to what extent should we leave it up to the physicians themselves to decide what they should do? Some members advocated a course of controlling everything down to the last detail, while others wanted little or no involvement at all on the part of the NETWORK.

    Ulrich and I were uncertain what to do and discussed what approach we should adopt both internally and with Synthesis Management, our advisers, who throughout this whole time had given us important strategic tips. We finally reached the conclusion that we should only intervene where individual members acted in breach of the national laws of their countries, but that we should not seek to regulate our members beyond what the national laws required of them. At the same time, however, we concurred with our members that the therapy only belonged in the hands of fully qualified doctors and should not be carried out by nurses, even in countries where the latter are allowed to do far more tasks than they are here in Germany. It should be pointed out, though, that NETWORK physicians can have their nurses trained by the NETWORK, provided it is the doctor who decides on application of the therapy and the nurse only carries out the practical treatment in accordance with the doctor’s instructions.

    In the same year, we were confronted by some doctors with the Brazilian “pig poster”. A poster was shown at a conference claiming that of 6 piglets treated with PPC, 2 had died after the injection. This was a typical example of how attempts were made to denigrate lipolysis therapy and influence opinion against it at that time: Right since 2004, this alleged “pig study” has consisted entirely of the poster, with no further publication ever being made. It appears that six piglets were injected once a week in high dosage with a Brazilian PPC compound (???) with an alcohol content of 50% (rather than 3.5%). The outcome of our investigations was that pigs are lacking an enzyme and therefore only have a limited ability to break down alcohol. We therefore assume that the death of the pigs was in fact not caused by PPC, which would indeed have been highly unusual.

    2005 was a year in which we, and myself in particular, were suffered through our own incaution and insensitivity. We continued to hold our workshops in London, but received emails from our members that British institutions were taking action against lipolysis. There was even talk of the possibility of a possible ban. What happened was that the MHRA (Medical Health Registration Agency) prohibited advertising for the therapy and the import of Lipostabil by physicians, while the MPS (Medical Protection Society), the state-run English insurer, refused all further insurance cover. So in mid-2005, our activities in the UK came to an abrupt end. The BACD, which was much better able to judge the legal situation in the country than we were, engaged a lawyer to represent its (and our) interests, while we mostly concentrated our efforts on obtaining international insurance cover. Lipolysis treatment in the UK almost came to a full stop. We saw dark forces at work, e.g. plastic surgeons concerned about losing their liposuction business, and engaged in conspiracy theories. Looking back from today’s vantage point, 
    I can say that this had mostly to do with providing cover for our own inability to handle the situation rationally and in a strategically intelligent manner. Without the active help and support of the BACD, we would not have been able to resolve this delicate situation, and I would once again like to express our most sincere gratitude for this to those in charge in the organization .

    We were given a second, and at least equally important lesson in Italy. Although we should have been warned by the events in the UK, we offered courses in Italy. At our second workshop in Rome, the Guardia die Sanita (Health Police) marched in, confiscated the stock of Lipostabil we had brought with us for the treatment demonstrations, and barred us from conducting any practical demonstrations. In this case, the conspiracy theory was not far from the truth: The Guardia had received an anonymous tip-off about the training course we were offering and had therefore sprung into action. Essentiale had been registered in Italy for several decades and had only recently been taken off the market. A little later, workshops were held by Italian physicians on the basis of our protocols and using Phosphatidylcolina produced by a number of pharmacies.

    Since that time, legality has been a pre-eminent issue in offering courses in other countries, with careful research and close contact to the official bodies becoming a matter of course. We ourselves were perfectly aware that the therapy did not present any danger if performed in accordance with the NETWORK protocols, but we simply had to bow to the national authorities and recognize that they had no alternative but to comply with their national laws and regulations. In this sensitive area, guerilla marketing would have been counterproductive.

    End of Part 2, to be continued ...


       Side Effect Management to top 

    The work of the NETWORK-Lipolysis is not a matter of simply preserving our achievements so far. The reports from our members are constantly giving us new ideas on how we can develop the therapy further.

    A main focus of the NETWORK’s efforts last year was on the side-effects that accompany the therapy: swelling, bruising, and pain during and after the injections.
    The goal of these activities is to make the treatment as pleasant as possible for the patients, without having any negative effect on the outcome. The known and expected side-effects are not serious, and the treatment also works when they are present. Nevertheless, we are not prepared to simply accept things as they are, but are constantly striving to make our treatment protocol better still.
    Many members have contributed their experience and views to the debate about new ways of managing the side-effects of lipolysis treatment, and numerous new approaches have been discussed and reviewed. We are currently engaged in sorting all these results and expect to be able to present a first comprehensive protocol which can be used in all countries by the time of our Members Meeting on 27 November during the M.A.S.T.E.R. Conference 2009 - FAT.

       Anesthesis C to top 

    Members of the NETWORK-Lipolysis were involved in the development of this new anaesthetic cream.

    In the field of dermatology and plastic surgery, newly developed surface treatment procedures (e.g. fractioned laser systems) make new and more exacting demands on an anaesthetic cream for use in minimally invasive treatments...

    The anaesthetic creams previously available contain only a small concentration of local anaesthetic such as lidocain or prilocain. Some products even require occlusive application for a period of 30 to 60 minutes. For the treatment methods referred to above, the anaesthetizing effect was simply not sufficient. These procedures require a product that is highly effective, quick-acting and easy-to-use, without the need for occlusion. A specification profile was therefore drawn up as the basis for the development of a new cream which would meet the requirements for a broad range of applications in the field of aesthetic medicine.

    Thanks to the experience of the dermatological members of the NETWORK and the pharmacists at the Steunpunt Apotheek Mierlo Hout (NL), it has been possible to develop an anaesthetic cream that is ideal for aesthetic therapies.
    Besides the carefully harmonized composition of the anaesthetic substances, of major importance in any anaesthetic cream is the base substance as this is responsible for ensuring the penetration of the active substances, the depth of penetration, the necessary time of action and the consistency of the product.
    The anaesthetic cream "Anesthesis C", which is produced and supplied by the Steunpunt Apotheek Mierlo Hout on prescription, fulfilled all the expectations of the medical practitioners when tested by them in practical trials.

    Test results:

    Very good (half-side comparison trials with industrial creams available on the market as well as creams made up to prescription)
    Speed of action:
    Very fast (on average approx. 15 minutes until readiness for the start of treatment)
    not necessary
    Open application without occlusion, wipes off very easily.
    Air-tight dispenser (contents 99% usable)
    Shelf life:
    On the basis of testing to date, Steunpunt Apotheek certifies a shelf life of 6 months.
    Field of application:
    For universal application in all minimally invasive aesthetic therapies.
    Renders the use of narcosis or sedation and facial blocks largely unnecessary, even in sensitive treatment areas

    In summary, therefore, it can be stated that "Anesthesis C" closes a major gap and now allows most minimally invasive therapies to be performed completely or large pain-free, to the benefit of the patient and practitioner alike.
    The NETWORK-Globalhealth recommends use of this cream to its members, and the trainers of the NETWORK-AestheticMeso and the Globalhealth Academy use this cream at their workshops in practical demonstrations of therapies such as botox®, fillers, aesthetic mesotherapy or peeling.

    Further information on the cream together with the opinions of the NETWORK members who took part in the trials can be found HERE.

       PPC in medicine to top 

    PPC – Polyenylphosphatidylcholine is the most important active ingredient in the elimination of unwanted cushions of fat. At the same time, this lecithin is a membrane therapeutic of the first rank. Dr. Hasengschwandtner and Dirk Brandl have viewed and summarized the existing literature on this topic...

    The detailed report can be found at this LINK

       New products + special offers to top 

    New products + special offers in June/July

    •    Needles - a worldwide innovation!!
    •    Multiinjectors -20% off
    •    Mesotherapy solutions/Cocktails

    Andreas Kambanas
    Tel: +49 - (0)2506 3061 914
    E-Mail: shop@netzwerk-lipolyse.de

    Needles     -   NETWORK EXCLUSIVE!

    Worldwide innovation!!
    meso-relle® 33G    (0,23mm x 4mm)  
    Box of 100 only €35.00

    The world’s thinnest needles (0.23mm x 4 mm) for aesthetic applications are now available in top quality through the NETWORK at an introductory price of only €35.00!  

    No needle could be finer! With these needles, the patient feels next to nothing. These high-quality needles have a special tapered tip and coating. Their high quality clearly distinguishes them from cheap imports from Asia which fail to live up to their promise. Make use of the benefits these needles offer - your patients will thank you for it!

    Special offer!!     
    meso-relle® 30G (0,30mm x 6mm) 
    Box of 100 only  €21.00 instead of €25.00


    go shopping...


    The multi-injector from meso-relle® -  20% off!

    meso-relle® - linear 3 or circular 5
    Box of 50 only €95.00 instead of €108.00 +P&P

    Special offer until 31 July 2009


    Buying through the NETWORK is worth it
    Mesotherapy solutions/Cocktails

    All solutions/cocktails are now permanently reduced in price by up to 50%.

    Because of the increasing volumes of orders received from you, we can now claim higher discounts from the suppliers.

       M.A.S.T.E.R. - Conference  -  FAT to top 

    The Globalhealth Academy’s M.A.S.T.E.R. Conference FAT is being held on 28 November in Bochum within the framework of the COSMEDICA. Interested physicians can book both events as a double package....

    The event is intended for all physicians working in the field of aesthetics who want to obtain a complete overview on the subject of fat; at the same time, we also want to introduce medical nutrition specialists to the possibilities of influencing the body contour using the resources of aesthetic medicine.

    For a small extra charge, all the other COSMEDICA events can be booked additionally. Especially the live demonstrations will be of interest for the colleagues who do not speak German.

    The M.A.S.T.E.R. Conference is embedded between the 5th International Members Meeting of the NETWORK-Lipolysis on Friday, 27 November, and the workshops (mesotherapy, injection lipolysis) being held on Sunday, 29 November.

    Our homepage www.master-conference.com provides all important information on the M.A.S.T.E.R. Conference FAT 2009, the first international congress on .... All You Ever Wanted to Know About FAT...

    We look forward to your visit.

    M.A.S.T.E.R. - Conference Logo

    NETWORK-Lipolysis Members Meeting

    Friday, 27 November 2009

    M.A.S.T.E.R. Conference FAT 2009 - 1st International Fat-Congress

    Saturday, 28 November 2009

    Workshops (in English language)

    • Full day introductory workshop on Injection-Lipolysis

    • Full day advanced workshop on Injection-Lipolysis (members only)

    • Aesthetic Mesotherapy - First presentation of the NETWORK-Standard in aesthetic mesotherapy

    Sunday, 29 November 2009

       Workshop-Report (Participant Satisfaction) to top 

    Since mid-2005, we have asked the participants in all our workshops to complete a feedback form afterwards. We now have nearly 700 feedbacks to evaluate. On a German school grading scale of 1 to 5 (1 = very good, 5 = fail), we have been awarded an average grade of 1.56. We are delighted that our training concept achieves such a positive result.....

    It goes without saying, however, that the NETWORK is not resting on its laurels. Instead, we are constantly striving to further improve the quality of the training in order to provide the participating physicians with the best possible practical training, independent of any outside interests, and through the membership of the NETWORK to offer them further support and a platform for interaction.


       Lipolysis "en route" - member lectures on conferences to top 
    If you want to get to know better what Lipolysis is about you can take the chance to visit one of the conferences below....


    WCAM 2009
    XVII World Congress of Aesthetic Medicine
    17 to 19th July 2009  -  
    Vancouver BC, Canada

    Dr. Linda Ptito, Montreal QC, Canada



    5 Continent Congress

    Lasers and Aesthetic Medicine on 5 Continents
    10 to 12th September 2009  -  
    Nice, France

    Dr. Klaus Fritz, Landau, Germany
    Skin surface treatment by different therapies

    Dr. Klaus Hoffmann, Bochum, Germany
    New study results on Injection-Lipolysis



    ECAAAM 2009

    2. European Congress on Anti-Aging & Aesthetic Medicine 2009
    15 to 17th October 2009  -  
    Mainz, Frankfurt - Germany

    Dr. Thomas Zimmemann, Heusenstamm, Germany



    WALA-Laser 2009
    World Academy of Laser Applications Congress
    in coalesce with the 1st Aesthetic & Anti-Aging Symposium

    18 to 21st October 2009  -  

    MR Dr. Franz Hasengschwandtner, Bad Leonfelden, Austria



    COSMEDICA 2009 
    & M.A.S.T.E.R. - Conference "FAT"
    27 to 29th November 2009  -  
    Bochum, Germany

    MR Dr. Franz Hasengschwandtner, Bad Leonfelden, Austria


    ... more to come
       Course schedule 2009 to top 
    Bild-Workshops Forthcoming introductory workshops....

      For programs and registration documents 
      please contact our Registrations Manager, Mr. Muechler
      +49 (0)25 06 / 30 61 922

    NETWORK-Lipolysis' Injection Lipolysis Therapy

    27 June 2009

      Hamburg, Germany (German language)

    04 July 2009

      Bad Leonfelden, Austria (German language)

    22 August 2009

      Dortmund, Germany (German language)

    12 September 2009

      Montréal, QUE - Canada (English language)

    19 September 2009

      Darmstadt (Frankfurt), Germany (German & English language)

    24 September 2009

      Riyadh, Saudi Arabia (English/Arabic)

    24 October 2009

      Munich, Germany (German language)

    29 November 2009

      Bochum, Germany (englisch)

    05 December 2009

      Dortmund, Germany (German language)

    Events for NETWORK-members

    27. Nov. 2009

    International member's meeting
    at the M.A.S.T.E.R. Conference - FAT
    Bochum, Germany (English language)

    29. November  2009

    Advanced course - Injection-Lipolysis (English language)
    at the M.A.S.T.E.R. Conference - FAT
    Bochum, Germany (English language)


    19-20 September 2009

    Aesthetic face composition by mesotherapy,
    botolinum toxine A, peelings and fillers 
    Frankfurt am Main, Deutschland (Englisch language)

    24 October 2009

    Skin surface treatment by different therapies (fractional laser, peelings etc.)
    Augsburg, Germany (German language)

    27-29 November 2009

    M.A.S.T.E.R. Conference - FAT
    Bochum, Germany (English language)

    29 November 2009

    Aesthetic Mesotherapy  -  The NETWORK-Protocol
    Bochum, Germany (English language)

    Newsletter-Information / Imprint
    NETWORK contact
    In case of questions please send us an e-mail to news@network-lipolysis.com or call us at  +49 (0)2506 / 3061901.
    You are also welcome to visit our website.
    NETWORK-Lipolysis c/o Lichtblick GmbH; Eschstr. 4; 48167 Münster, Germany
    Competent County Court: Münster, HRB 8088; Managing Director: Ulrich Bunzek


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